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VanBUG Seminar Series: Sara Mostafavi, UBC
Webcast Link: http://vidyoreplay.computecanada.ca/replay/webcastShow.html?key=TAKdbjoDvIqKdLn
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Technological advances in the last decade now enable us to measure parts of biological systems at various resolutions, for example, at the genome, epigenome, and the transcriptome levels. These data provide an opportunity to build mechanistic models of gene regulatory networks, and further to infer dysregulation of these networks that underlie complex diseases and traits. In this talk, I’ll present computational and statistical approaches for:
a) combining multiple types of genomics data to better understand dysregulatory effects in a complex psychiatry disorder, namely major depression;
b) inferring gene regulatory networks across multiple tissues and cell types, and identifying the impact of inter-individual genetic variation on these networks.
Sara Mostafavi is an Assistant Professor at the Departments of Statistics and Medical Genetics at UBC. Sara did her PhD in Computer Science at the University of Toronto, where she focused her research in the area of machine learning and computational biology. She then did a postdoctoral fellowship at Stanford’s Department of Computer Science, followed by a research fellowship at Harvard Medical School. Sara’s research focuses on developing and using machine learning and statistical methods for combining high dimensional genomics data, in order to reconstruct gene regulatory networks, and to identify genes and pathways underlying a variety of complex neuropsychiatric disorders.
Trainees are invited to meet with the VanBUG speaker for open discussion of both science and career paths. This takes place 4:30-5:30pm in either the Boardroom or Lunchroom on the ground floor of the BCCRC. Also, each seminar is followed by complementary pizza, refreshments, and great networking.
- Elizabeth Chun, PhD student (Dr. Marco Marra lab)
VanBUG (Vancouver Bioinformatics Users Group) is an association of researchers, other professionals and students in the BC Lower Mainland who have an interest in the field of bioinformatics. VanBUG meets on the second Thursday of every month from September through April. Research presentations by bioinformatics leaders, students and industry representatives are followed by networking over pizza and refreshments Meetings are held in the Gordon and Leslie Diamond Family Theatre, BC Cancer Research Centre, 675 West 10th Avenue at 6:00 pm and are free and open to all.